Workshop: Implementation strategies for delivering RTS,S in countries with seasonal transmission

Université de Thiès, Senegal
Workshop on implementation strategies for the RTS,S/AS01 vaccine in settings with seasonal malaria

Overview

January 2023

Representatives from the National Malaria Programmes (NMPs) and Expanded Programmes of Immunization (EPI) from 13 African countries in West and Central Africa participated in a recent workshop to consider implementation strategies for delivering the RTS,S/AS01 malaria vaccine. This included discussions on the need for implementation research to investigate potential strategies.

The workshop was co-hosted by the OPT-SMC initiative and TDR through the Access and Delivery Partnership (ADP), with technical input from Gavi, the WHO Malaria Vaccine Implementation Programme, the WHO Regional Office for Africa, PATH and other stakeholders.

Areas across Africa where seasonal malaria chemoprevention (SMC) is implemented (OPT-SMC initiative).

Areas across Africa where seasonal malaria chemoprevention (SMC) is implemented (OPT-SMC initiative).

Workshop objectives

To review the current evidence on the RTS,S malaria vaccine in terms of evidence on vaccine efficacy and impact, and safety.
To share experiences across countries that have introduced the RTS,S vaccine in routine child vaccination services in Ghana, Kenya, Malawi, and SMC-implementing countries that are considering malaria vaccine introduction, to better understand the practical implementation challenges and lessons learned for vaccine introduction.
To discuss regulatory and supply management issues when introducing the RTS,S vaccine in the health systems.
To discuss implementation strategies and mode of delivery in countries with seasonal transmission and low or moderate EPI coverage during the 1st and 2nd year of life.
To discuss the operational/implementation research needs to document the implementation of RTS,S in terms of effectiveness, acceptability, feasibility, safety and coverage.

“In areas of seasonal transmission where we achieved high coverage of seasonal malaria chemoprevention and long-lasting insecticidal nets, the additional implementation of the RTS,S malaria vaccine could help to reduce 92% malaria burden and accelerate the pathway towards malaria elimination.”

-Professor Jean-Louis Ndiaye, Université de Thiès, Senegal and host of the workshop

Université de Thiès, Senegal
Professor Jean-Louis Ndiaye

Workshop documents

Short report in English and French

Presentations

Title	Type	Size
01_OPT-SMC update - SMC research	pdf	756 KB	Download
02_RTS,S/AS01 malaria vaccine current evidence, including efficacy, safety, feasibility and impact and update on R21/Matrix-M malaria vaccine	pdf	1569 KB	Download
03_Optimising the use of the RTS,S/AS01 malaria vaccine in the control of seasonal malaria	pdf	4263 KB	Download
04_Malaria vaccine supply situation & Framework for allocation of limited vaccine	pdf	3582 KB	Download
05_Gavi Malaria Vaccine Programme update	pdf	1237 KB	Download
06_Discussion: Practical considerations for RTS, S malaria vaccine supply chain	pdf	559 KB	Download
07_Regulatory consideration for introduction of RTS, S in SMC countries	pdf	649 KB	Download
08_Overview of SMC: Target population, eligible geographic area, model of delivery, integration with other preventive measures	pdf	901 KB	Download
09_01_Lessons Learnt implementing Malaria Vaccine in Kenya	pdf	1779 KB	Download
09_02_Malawi country experience	pdf	1441 KB	Download
09_03_Lessons learned and practical experience from pilot introduction of the RTS,S malaria vaccine in Ghana	pdf	740 KB	Download
10_Facilitators and Barriers to Update of the RTS,S/AS01Malaria Vaccine	pdf	847 KB	Download
11_Malaria vaccine delivery considerations in seasonal transmission settings	pdf	3869 KB	Download
12_01_New vaccine post-introduction evaluation (PIE)	pdf	1040 KB	Download
12_02_Findings- Malaria Vaccine Implementation Programme (MVIP) Post Introduction Evaluation (PIE) In Ghana	pdf	437 KB	Download
13_Strengthening the evidence for policy on the RTS,S/AS01 malaria vaccine	pdf	2330 KB	Download
14_Implementation questions and funding for evaluation and implementation research questions	pdf	1370 KB	Download