The quality management system outlined in this Handbook will provide institutions and researchers with the necessary tools for the implementation and monitoring of quality practices in their research, thus promoting the credibility and acceptability of their work. The handbook highlights non-regulatory practices that can be easily institutionalised with very little extra expense.

This handbook is designed as an aid for those countries wishing to upgrade their laboratories to GLP status. Based on the Organisation for Economic Cooperation and Development (OECD) principles of GLP, the aim of the handbook is to provide laboratories and trainers in disease-endemic countries with the necessary technical information for implementing GLP programmes.

This manual provides resource material for good laboratory practice (GLP) training. It is based on the Organisation for Economic Cooperation and Development (OECD) principles of good laboratory practice (GLP), which are recognized as the international standard for GLP.

Compliance with these guidelines will allow clinical laboratories to ensure that safety and efficacy data is repeatable, reliable, auditable and easily reconstructed in a research setting. GCLP guidelines set a standard for compliance by laboratories involved in the analysis of samples from TDR-supported clinical trials.